CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1943
Family Name Muscarinic acetylcholine receptor M1 and Muscarinic acetylcholine receptor M4 ligand 6-fluoro-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00329024 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 4 and Muscarinic acetylcholine receptor M1 Binder Superfamily
Class Class 3454

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 1
Cannabinoid receptor 2 ligand SureCN738026 family 5 68
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 3
5-hydroxytryptamine receptor 4 ligand 6-fluoro-N-[[1-[(4-hydro... 1 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 3 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-cyclo... 3 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 3 5
Cannabinoid receptor 2 ligand SureCN738244 family 1 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 2 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 0
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide de... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00329022 CHEMBL1223754 Bioactive 6-fluoro-5-methyl-3-[1-(1-methyl-4-propoxycyclohexyl)piperidin-4-yl]-1H-benzimidazol-2-one
CFAMM00329020 CHEMBL2146599 Bioactive 5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
CFAMM00329024 CHEMBL1223753 Bioactive 6-fluoro-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27399 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543