CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19447
Family Name Histamine H3 receptor ligand 5-(3-bromophenyl)-2-[2-(1H-imidazol-5-yl)ethylsulfanyl]-1H-imidazole family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00451895 Functional Category Bioactive
Superfamily Beta-lactamase and Histamine H3 receptor Binder Superfamily 7
Class Class 392

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Histamine H3 receptor ligand SureCN7853275 family 2 5
Sterol O-acyltransferase 1 inhibitor 1-(2,4-difluorophenyl)-3-... 8 90
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 6 3
Acyl-CoA:cholesterol acyltransferase and Sterol O-acyltransfer... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00451895 CHEMBL86458 Bioactive 5-(3-bromophenyl)-2-[2-(1H-imidazol-5-yl)ethylsulfanyl]-1H-imidazole
CFAMM00451899 CHEMBL87911 Bioactive 2-[2-(1H-imidazol-5-yl)ethylsulfanyl]-5-(3-nitrophenyl)-1H-imidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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