CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19463
Family Name Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 4-(5,7-dioxopyrrolo[3,4-b]pyridin-6-yl)-3-fluorobenzenesulfonamide family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00451943 Functional Category Bioactive
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 4 Binder Superfamily 20
Class Class 845

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
M-phase inducer phosphatase 3 Inhibitor NSC-663284 Family 1 12
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 2 9
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
Histamine H3 receptor ligand SureCN1857507 family 1 4
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3-fluo... 6 4
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 4-chlo... 1 1
Integrin alpha-V inhibitor (2R)-3-(pyridine-3-carbonylamino)-2... 1 0
Caspase-3 inhibitor Inhibitor 55 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00451943 CHEMBL88120 Bioactive 4-(5,7-dioxopyrrolo[3,4-b]pyridin-6-yl)-3-fluorobenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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