CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19477
Family Name Calpain-1 catalytic subunit and Cathepsin B inhibitor (2R)-N-[(2S)-6-(benzenesulfonamido)-1-oxohexan-2-yl]-2-(methanesulfonamido)-3-phenylmethoxypropanamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00451974 Functional Category Bioactive
Superfamily Calpain-1 catalytic subunit and Cathepsin B Binder Superfamily 2
Class Class 1181

Cousin Family NamesSeedsMembers
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cruzipain Inhibitor WRR-204 Family 18 35
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Cathepsin B and Cathepsin S Inhibitor Cbz-ile-leu-ala-leuvsme ... 12 14
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(1-me... 3 8
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(2-th... 2 5
Growth hormone secretagogue receptor type 1 ligand SureCN63170... 1 1
Cathepsin S and Cathepsin L1 inhibitor benzyl N-[(2S)-1-oxo-1-... 2 2
Carbonic anhydrase 2 inhibitor benzyl 2-[[2-[[(2S)-3-phenyl-2-... 2 9
Calpain-1 catalytic subunit and Cathepsin B inhibitor [(3R,5S)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00451974 CHEMBL89100 Bioactive (2R)-N-[(2S)-6-(benzenesulfonamido)-1-oxohexan-2-yl]-2-(methanesulfonamido)-3-phenylmethoxypropanamide
CFAMM00451976 CHEMBL90661 Bioactive (2R)-N-[(2S)-1-oxo-3-phenylpropan-2-yl]-3-phenylmethoxy-2-(thiophen-2-ylsulfonylamino)propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27063 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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