CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19486
Family Name Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor ionotropic, NMDA 2A ligand SureCN6534335 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00452015 Functional Category Bioactive
Superfamily D(2) dopamine receptor and Methionine--tRNA ligase Binder Superfamily
Class Class 409

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Phospholipase A2 Inhibitor Quinacrine Family 13 95
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Corticotropin-releasing factor receptor 1 Ligand Cp-316,311 Fa... 5 74
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
Nicotinic acetylcholine receptor alpha2 / alpha3 Ligand Ibogai... 3 21
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Acetylcholinesterase Inhibitor Velnacrine Family 2 29
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
D(2) dopamine receptor Ligand SLV-314 Family 19 69
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 7 11
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 2
Corticotropin-releasing factor receptor 1 ligand AGN-PC-074YQD... 1 5
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 36 18
Glucocorticoid receptor ligand 4-fluoro-2-[5,5,5-trifluoro-4-h... 3 9
Melanin-concentrating hormone receptor 1 and Cytochrome P450 3... 8 2
Prelamin-A/C inhibitor 1-[(3,4-dimethoxyphenethyl)amino]-3-(1H... 1 2
Hypoxia-inducible factor 1-alpha and Lethal factor inhibitor C... 1 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(2-... 3 3
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
Coagulation factor X and Prothrombin inhibitor AGN-PC-0759SH f... 5 4
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 0
Somatostatin receptor type 2 ligand SureCN4313450 family 2 25
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Retinoic acid receptor RXR-alpha ligand (E)-3-[3-(3,5-ditert-b... 5 5
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 3 0
Corticotropin-releasing factor receptor 1 ligand 2-(2-ethyl-4,... 4 9
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 5
Acetylcholinesterase and Butyrylcholinesterase inhibitor (E)-3... 4 5
Cholinesterase and Acetylcholinesterase inhibitor 6-[2-methoxy... 12 6
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 6 4
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 4 4
Corticotropin-releasing factor receptor 1 ligand 3-ethyl-1-(2-... 5 15
C5a anaphylatoxin chemotactic receptor 1 ligand 2-(2,6-diethyl... 3 5
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Gonadotropin-releasing hormone receptor ligand 2-[2-(4-methoxy... 1 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PJ... 4 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Protein kinase C theta type and Protein kinase C delta type in... 10 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 18 0
Sodium-dependent serotonin transporter and D(2) dopamine recep... 4 0
Reverse transcriptase/RNaseH inhibitor AC1L9RKO family 2 17
Dipeptidyl peptidase 4 inhibitor 2-[3-(aminomethyl)-4-(4-fluor... 3 0
Cytochrome P450 2D6 inhibitor AGN-PC-075CGG family 1 2
Coagulation factor VII and Tissue factor inhibitor 5-azaindole... 4 3
Beta-3 adrenergic receptor ligand SureCN7133396 family 1 0
Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-amin... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00452015 CHEMBL89765 Bioactive SureCN6534335

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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