CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1949
Family Name Muscarinic acetylcholine receptor M1 and Muscarinic acetylcholine receptor M5 ligand 3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-2-oxo-1,3-benzoxazole-5-carbonitrile family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00271749 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor M1 and Muscarinic acetylcholine receptor M3 Binder Superfamily 2
Class Class 1071

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 3 27
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Amyloid beta A4 protein Inhibitor SB-13 Family 1 2
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
Histamine H3 receptor ligand 5-[4-[3-[(2R)-2-methylpyrrolidin-... 2 3
Translocator protein inhibitor N-methyl-2-[2-oxo-5-[4-(trifluo... 9 3
Urotensin-2 receptor and Cytochrome P450 3A4 ligand 5-chloro-3... 2 1
Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[(4-hy... 1 5
Neuronal acetylcholine receptor subunit alpha-7 ligand (5R)-3-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00329076 CHEMBL1223862 Bioactive 3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-5-methoxy-1,3-benzoxazol-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26858 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543