CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19497
Family Name Type-1 angiotensin II receptor ligand 2-[[(5-ethylpyrazolo[1,5-a]pyrimidin-7-yl)amino]methyl]-5-(2H-tetrazol-5-yl)dibenzo[1,2-e:1',2'-f][7]annulen-11-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00452035 Functional Category Bioactive
Superfamily Hepatocyte growth factor receptor and Type-1 angiotensin II receptor Binder Superfamily
Class Class 2684

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Forasartan Family 3 253
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 5 129
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Hepatocyte growth factor receptor Ligand MK-8033 Family 19 42
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
PHA848125 family 13 138
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Progesterone receptor Ligand GSK-325971A Family 1 13
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZYJE fa... 15 5
Sphingosine 1-phosphate receptor 1 ligand SureCN3029336 family 4 8
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Mitogen-activated protein kinase 14 inhibitor SureCN3632376 fa... 10 5
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 5 1
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Smoothened homolog inhibitor SureCN1091571 family 2 2
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Adenosine receptor A3 and Adenosine receptor A2a ligand SureCN... 8 7
Mitogen-activated protein kinase 14 inhibitor 3mvm family 6 1
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
DNA-dependent protein kinase catalytic subunit and Tyrosine-pr... 2 10
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Mitogen-activated protein kinase kinase kinase kinase 5 and Du... 1 18
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 3
Aurora kinase A inhibitor AGN-PC-00EHLC family 1 0
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 1 4
Hepatocyte growth factor receptor ligand 9-[[3-methoxypropyl(m... 17 2
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
TGF-beta receptor type-1 ligand 3-[[3-(6-methylpyridin-2-yl)-4... 1 0
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Hepatocyte growth factor receptor ligand 5-[[6-(1-methylpyrazo... 4 0
Hepatocyte growth factor receptor ligand 5-[(6-phenyl-[1,2,4]t... 6 2
Mitogen-activated protein kinase 14 inhibitor ethyl N-[4-[5-(m... 5 2
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
DNA gyrase subunit B inhibitor 5-[2-(ethylcarbamoyl)-4-[3-(tri... 2 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 12 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Casein kinase II subunit alpha inhibitor 2pvj family 3 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Mast/stem cell growth factor receptor Kit and Epithelial disco... 3 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 6 0
Epithelial discoidin domain-containing receptor 1 and Mast/ste... 1 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Casein kinase II subunit alpha inhibitor CHEMBL401945 family 12 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Alpha-1B adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 5
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 5 1
Aurora kinase A and Aurora kinase B inhibitor N-[(3E)-3-[5-(mo... 3 2
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Hepatocyte growth factor receptor ligand 1-methyl-N-[2-(1-meth... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00452035 CHEMBL90513 Bioactive 2-[[(5-ethylpyrazolo[1,5-a]pyrimidin-7-yl)amino]methyl]-5-(2H-tetrazol-5-yl)dibenzo[1,2-e:1',2'-f][7]annulen-11-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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