CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1951
Family Name Adenosine receptor A1 and Adenosine receptor A2b ligand 2-amino-6-(1H-imidazol-2-ylmethylsulfanyl)-4-(4-methoxyphenyl)pyridine-3,5-dicarbonitrile family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00329082 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Histamine H3 receptor Binder Superfamily
Class Class 1249

Cousin Family NamesSeedsMembers
Tyrosine kinase Inhibitor PKI166 Family 17 198
Histamine H3 receptor Ligand 4-(3-phenoxy-propyl)-1h-imidazole... 26 142
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 1 9
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... 1 0
Casein kinase I isoform delta and Mitogen-activated protein ki... 3 18
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 2 10
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Histamine H3 receptor ligand AGN-PC-075YXY family 1 4
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00329083 CHEMBL122622 Bioactive SureCN13914330
CFAMM00329082 CHEMBL122396 Bioactive 2-amino-6-(1H-imidazol-2-ylmethylsulfanyl)-4-(4-methoxyphenyl)pyridine-3,5-dicarbonitrile
CFAMM00329081 CHEMBL122806 Bioactive 2-amino-4-(3-hydroxyphenyl)-6-(1H-imidazol-2-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
CFAMM00329080 CHEMBL125979 Bioactive AGN-PC-005EW0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26825 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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