CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19512
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[3,4-dioxo-2-(propylamino)cyclobuten-1-yl]amino]-3-(4-pyrimidin-2-yloxyphenyl)propanoic acid family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00452063 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrimidin-4-ylamino)benzoic Acid Superfamily
Class Class 850

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 6
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 4 40
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(dime... 2 2
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN2059024 f... 6 3
Xanthine dehydrogenase/oxidase inhibitor 4-[[4-(2-aminopyrimid... 3 16
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 12 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 1 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 12
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 21
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 3 1
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00452064 CHEMBL9884 Bioactive (2S)-2-[[2-(diethylamino)-3,4-dioxocyclobuten-1-yl]amino]-3-(4-pyrimidin-2-yloxyphenyl)propanoic acid
CFAMM00452063 CHEMBL9173 Bioactive (2S)-2-[[3,4-dioxo-2-(propylamino)cyclobuten-1-yl]amino]-3-(4-pyrimidin-2-yloxyphenyl)propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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