CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19541
Family Name Melatonin receptor type 1B and Melatonin receptor type 1A ligand SureCN8126456 family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00273263 Functional Category Bioactive
Superfamily Nuclear receptor coactivator 3 and Sphingosine 1-phosphate receptor 1 Ligand Gnf-pf-78 Superfamily
Class Class 2009

Cousin Family NamesSeedsMembers
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Neuronal acetylcholine receptor subunit alpha-4 Ligand TC-5619... 3 61
Vascular endothelial growth factor receptor 2 Ligand E 7080 Fa... 7 17
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Smoothened homolog Inhibitor LDE225 Family 3 76
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Cytochrome P450 3A4 Inhibitor 3-(5-((methylthio)methyl)furan-2... 4 14
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Renin Inhibitor CP-305202 Family 9 30
Nuclear receptor coactivator 3 and Sphingosine 1-phosphate rec... 1 1
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 1 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
cAMP-dependent protein kinase type II-alpha regulatory subunit... 2 4
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Neuronal acetylcholine receptor subunit alpha-7 ligand 2-[3-cy... 2 5
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
Acetylcholinesterase and Cholinesterase inhibitor (2Z)-5-metho... 4 23
Cathepsin S and Cathepsin K inhibitor N-[(2S)-3-(1-methylcyclo... 2 0
Cytochrome P450 2C19 and Inositol monophosphatase 1 inhibitor ... 1 0
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 8 10
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 1 14
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 4 11
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Beta-3 adrenergic receptor ligand 6-[4-[2-[[(2S)-3-[(3,3-dimet... 6 7
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 5 ... 1 0
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 4 4
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Cathepsin K and Cathepsin L1 inhibitor AC1NR9VX family 2 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 3 15
Substance-P receptor ligand SureCN2139814 family 7 7
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 0
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 6 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Collagenase 3 inhibitor SureCN1316041 family 4 3
Sodium-dependent serotonin transporter inhibitor SureCN5477150... 4 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 12
Tyrosine-protein kinase JAK3 and Activated CDC42 kinase 1 inhi... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26825 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543