CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19562
Family Name 5-hydroxytryptamine receptor 1A ligand AGN-PC-074R8E family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00452234 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Binder Superfamily 3
Class Class 769

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Doxepin Family 8 89
Muscarinic acetylcholine receptor Ligand Methantheline Family 6 8
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
5-hydroxytryptamine receptor 1A ligand (3S)-3-[4-(7,9-dioxo-8-... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 14 1
Renin inhibitor N-[(2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00452234 CHEMBL96999 Bioactive AGN-PC-074R8E
CFAMM00452232 CHEMBL97857 Bioactive SureCN8823628

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27398 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543