CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19582
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand SureCN10715388 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00452282 Functional Category Bioactive
Superfamily Ras-related protein Rab-9A and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Binder Superfamily
Class Class 3394

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Ibrutinib family 2 27
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Corticotropin-releasing factor receptor 1 Ligand BMS-561388 Fa... 10 16
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-072YXQ ... 2 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Su... 2 16
Epidermal growth factor receptor and Cyclin-dependent kinase 1... 3 4
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
Translocator protein inhibitor AGN-PC-080ILF family 9 3
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 5
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 4
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 6
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 5
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 6
Neuropeptide Y receptor type 1 ligand CP-671906 family 10 0
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 4 4
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Estrogen receptor and Estrogen receptor beta ligand 4-[3-[4-(2... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Type-1 angiotensin II receptor ligand 2-ethyl-6-methoxy-N-[[4-... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 3
Adenosine receptor A1 and Adenosine receptor A2a ligand 7-meth... 2 0
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
Adenosine receptor A2a ligand AGN-PC-077RYH family 16 5
Corticotropin-releasing factor receptor 1 ligand AGN-PC-068CCI... 3 0
Hepatocyte growth factor receptor ligand AGN-PC-077K0V family 3 0
Hepatocyte growth factor receptor ligand 4-[(6-thiophen-2-yl-[... 4 0
Aurora kinase A and Glycogen synthase kinase-3 beta inhibitor ... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00452282 CHEMBL98962 Bioactive SureCN10715388
CFAMM00452281 CHEMBL99831 Bioactive AGN-PC-0006WH

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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