CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19622
Family Name Aldose reductase inhibitor SureCN8804611 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00452439 Functional Category Bioactive
Superfamily Aldose reductase and Prostaglandin G/H synthase 2 Binder Superfamily
Class Class 3129

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Neuromedin-K receptor Ligand Osanetant Family 38 192
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 2 23
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [2... 2 4
Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 2
Prelamin-A/C and Ras-related protein Rab-9A inhibitor CHEMBL15... 1 7
Prothrombin inhibitor AGN-PC-09QJ23 family 2 5
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-chloro-5-... 3 1
Histamine H3 receptor ligand AGN-PC-01WA6E family 10 1
Sodium-dependent dopamine transporter and Transporter inhibito... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00452437 CHEMBL59663 Bioactive 2-[(4-chlorophenyl)methyl]spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'-tetrone
CFAMM00452439 CHEMBL10382 Bioactive SureCN8804611

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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