CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19623
Family Name Metabotropic glutamate receptor 2 ligand SureCN6733905 family
No. of Seeds 11 No. of Other Members 8
Family Centroid CFAMM00452441 Functional Category Bioactive
Superfamily and Menin Binder Superfamily
Class Class 198

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(4-f... 2 5
Prothrombin inhibitor AGN-PC-074A4O family 2 7
Prothrombin inhibitor AGN-PC-073FOY family 2 1


External ID

Functional Category

Molecule Name

CFAMM00452444 CHEMBL107114 Bioactive SureCN6732978
CFAMM00452450 CHEMBL105193 Bioactive SureCN6731974
CFAMM00452443 CHEMBL105151 Bioactive AGN-PC-044KFO
CFAMM00452455 CHEMBL105296 Bioactive 2,2,2-trifluoro-N-(3-pentan-2-yloxyphenyl)-N-(pyridin-3-ylmethyl)ethanesulfonamide
CFAMM00452448 CHEMBL107948 Bioactive SureCN6731022
CFAMM00452441 CHEMBL104190 Bioactive SureCN6733905
CFAMM00452454 CHEMBL322588 Bioactive SureCN6739416
CFAMM00452447 CHEMBL322465 Bioactive 2,2,2-trifluoro-N-(pyridin-3-ylmethyl)-N-[3-(2,2,2-trifluoroethoxy)phenyl]ethanesulfonamide
CFAMM00452453 CHEMBL321746 Bioactive SureCN6730996
CFAMM00452440 CHEMBL323541 Bioactive AGN-PC-074V3K
CFAMM00452446 CHEMBL321968 Bioactive cyPPTS

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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