CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1970
Family Name Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter inhibitor SureCN413470 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00329131 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Prostaglandin G/H synthase 2 Binder Superfamily
Class Class 643

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
D(3) dopamine receptor Ligand SB-277011 Family 13 178
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 1-(9h-... 4 25
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Transient receptor potential cation channel subfamily V member... 6 23
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Endothelin B receptor Ligand IRL-2500 Family 34 87
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Cathepsin K inhibitor [(3S)-1-(1H-indole-6-carbonyl)-4,4-dimet... 2 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 10 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 18
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 9 3
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Interstitial collagenase and Matrilysin inhibitor (2S,3R)-N,2-... 3 1
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... 4 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 18 3
Cytochrome P450 2D6 and Cytochrome P450 2C19 inhibitor Demethy... 1 4
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 3 1
High affinity nerve growth factor receptor and BDNF/NT-3 growt... 4 3
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26825 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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