CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19709
Family Name RAC-alpha serine/threonine-protein kinase and Mast/stem cell growth factor receptor Kit ligand 5-[2-[[(2S)-2-amino-3-[4-(trifluoromethyl)phenyl]propyl]amino]-1,3-thiazol-5-yl]-1,3-dihydroindol-2-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00452793 Functional Category Bioactive
Superfamily RAC-alpha serine/threonine-protein kinase and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 1481

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing... 3 16
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 8
Protease and Capsid scaffolding protein inhibitor AC1LAC7K family 2 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 3
Prothrombin and Trypsin-1 inhibitor (2S)-1-[(2R)-2-amino-3,3-d... 1 3


External ID

Functional Category

Molecule Name

CFAMM00452794 CHEMBL1082016 Bioactive 5-[2-[[(2S)-2-amino-3-[4-(trifluoromethyl)phenyl]propyl]amino]-1,3-thiazol-5-yl]-3-methyl-1H-benzimidazol-2-one
CFAMM00452793 CHEMBL1081831 Bioactive 5-[2-[[(2S)-2-amino-3-[4-(trifluoromethyl)phenyl]propyl]amino]-1,3-thiazol-5-yl]-1,3-dihydroindol-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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