CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19745
Family Name Glycogen phosphorylase, liver form inhibitor 2-[(1R,2R)-2-[(5-chloro-6-fluoro-1H-indole-2-carbonyl)amino]-2,3-dihydro-1H-inden-1-yl]acetic acid family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00452950 Functional Category Bioactive
Superfamily Glycogen phosphorylase, liver form Binder Superfamily
Class Class 3857

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
HIV protease Inhibitor Saquinavir Family 64 428
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... 4 36
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Reverse transcriptase Inhibitor IDX899 Family 2 118
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 3 14
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Cannabinoid receptor 1 ligand 5-cyano-1-[(3,5-dichlorophenyl)m... 2 0
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Coagulation factor X and Prothrombin inhibitor N,1-bis[(3-carb... 1 1
Poly [ADP-ribose] polymerase 1 inhibitor SureCN4998361 family 1 1
Translocator protein inhibitor N,N-dibutyl-2-(7-chloro-2-pheny... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Neuromedin-K receptor ligand AGN-PC-00GCXP family 3 2


External ID

Functional Category

Molecule Name

CFAMM00452951 CHEMBL1086237 Bioactive SureCN4145951
CFAMM00452950 CHEMBL1084229 Bioactive 2-[(1R,2R)-2-[(5-chloro-6-fluoro-1H-indole-2-carbonyl)amino]-2,3-dihydro-1H-inden-1-yl]acetic acid
CFAMM00452952 CHEMBL1083942 Bioactive SureCN4143253

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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