CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19783
Family Name Poly [ADP-ribose] polymerase 1 inhibitor 3-(2,4-dioxo-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-1-yl)-N-[2-oxo-2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]propanamide family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00453086 Functional Category Bioactive
Superfamily Calcitonin gene-related peptide type 1 receptor and Survival motor neuron protein Binder Superfamily
Class Class 1600

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Histamine H3 receptor ligand 1-[1-[1-[(2-aminopyridin-4-yl)met... 16 9
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 8 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 7 2
Glucokinase inhibitor (2S)-2-(4-cyclobutylsulfonyl-2-oxopyridi... 2 8
Calcitonin gene-related peptide type 1 receptor ligand N-[1-me... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00453083 CHEMBL410733 Bioactive N-[2-[4-(3-aminopyridin-2-yl)piperazin-1-yl]-2-oxoethyl]-3-(2,4-dioxo-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-1-yl)propanamide
CFAMM00453082 CHEMBL110178 Bioactive 3-(2,4-dioxo-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-1-yl)-N-[2-oxo-2-(4-pyridin-4-ylpiperazin-1-yl)ethyl]propanamide
CFAMM00453081 CHEMBL419020 Bioactive 3-(2,4-dioxo-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-1-yl)-N-[2-oxo-2-[4-[3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]ethyl]propanamide
CFAMM00453086 CHEMBL430707 Bioactive 3-(2,4-dioxo-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-1-yl)-N-[2-oxo-2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]propanamide
CFAMM00453085 CHEMBL108623 Bioactive 3-(2,4-dioxo-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-1-yl)-N-[2-oxo-2-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]ethyl]propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27509 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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