CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19785
Family Name Cholesteryl ester transfer protein inhibitor [(5S)-2,4-dicyclopentyl-5-hydroxyspiro[6,8-dihydro-5H-quinoline-7,1'-cyclobutane]-3-yl]-[4-(trifluoromethyl)phenyl]methanone family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00453092 Functional Category Bioactive
Superfamily Retinoic acid receptor alpha Ligand LG100268 Superfamily
Class Class 946

Cousin Family NamesSeedsMembers
Cholesteryl ester transfer protein inhibitor SureCN712339 family 1 28


External ID

Functional Category

Molecule Name

CFAMM00453088 CHEMBL1086637 Bioactive [(5S)-4-cyclohexyl-5-hydroxy-2-propan-2-ylspiro[6,8-dihydro-5H-quinoline-7,1'-cyclobutane]-3-yl]-[4-(trifluoromethyl)phenyl]methanone
CFAMM00453092 CHEMBL1087412 Bioactive [(5S)-2,4-dicyclopentyl-5-hydroxyspiro[6,8-dihydro-5H-quinoline-7,1'-cyclobutane]-3-yl]-[4-(trifluoromethyl)phenyl]methanone
CFAMM00453091 CHEMBL1087411 Bioactive SureCN4579328

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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