CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19802
Family Name Mitogen-activated protein kinase 14 and Mitogen-activated protein kinase 11 inhibitor SureCN5257721 family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00453156 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 11 and Mitogen-activated protein kinase 14 Binder Superfamily 4
Class Class 1532

Cousin Family NamesSeedsMembers
Glycogen synthase kinase-3 beta Inhibitor N-(6-(pyridin-4-yl)-... 4 23
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 1 7
Aurora kinase B inhibitor AGN-PC-07ZZ0Y family 2 12
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
Polycystin-2 and Serine/threonine-protein kinase D1 inhibitor ... 4 12
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 3 11
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Mitogen-activated protein kinase 10 and Transcription factor A... 4 4
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 3 3
Mitogen-activated protein kinase 8 inhibitor N-[4-[4-[2-(cyclo... 1 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 6 4


External ID

Functional Category

Molecule Name

CFAMM00453156 CHEMBL1090174 Bioactive SureCN5257721
CFAMM00453153 CHEMBL1092001 Bioactive 4-[3-(4-chlorophenyl)-5-[1-(oxolan-3-yl)piperidin-4-yl]-1H-pyrazol-4-yl]pyrimidine
CFAMM00453158 CHEMBL1089172 Bioactive (1S,2S)-2-[4-[3-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]piperidin-1-yl]cyclopentan-1-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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