CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19811
Family Name Poly [ADP-ribose] polymerase 1 inhibitor SureCN8058778 family
No. of Seeds 13 No. of Other Members 4
Family Centroid CFAMM00453212 Functional Category Bioactive
Superfamily Collagenase 3 and 72 kDa type IV collagenase Binder Superfamily 3
Class Class 2533

Cousin Family NamesSeedsMembers
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Renin Inhibitor Ro-66-1168 Family 10 30
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor AGN-PC-007ZS... 3 3
Adenosine receptor A2b and Adenosine receptor A1 ligand AGN-PC... 1 2


External ID

Functional Category

Molecule Name

CFAMM00453216 CHEMBL1090019 Bioactive SureCN8045810
CFAMM00453224 CHEMBL1093610 Bioactive SureCN8049710
CFAMM00453215 CHEMBL1089713 Bioactive SureCN8038190
CFAMM00453223 CHEMBL1092778 Bioactive SureCN8055566
CFAMM00453213 CHEMBL1092144 Bioactive SureCN8053551
CFAMM00453228 CHEMBL1094039 Bioactive 9-(1-propylpiperidin-4-yl)oxy-1,2,4,6-tetrahydrothiopyrano[3,4-c]quinolin-5-one
CFAMM00453221 CHEMBL1091454 Bioactive 9-(1-pentylpiperidin-4-yl)oxy-1,2,4,6-tetrahydrothiopyrano[3,4-c]quinolin-5-one
CFAMM00453212 CHEMBL1092145 Bioactive SureCN8058778
CFAMM00453227 CHEMBL1092777 Bioactive SureCN8038194
CFAMM00453220 CHEMBL1090020 Bioactive SureCN8049815
CFAMM00453211 CHEMBL1092143 Bioactive 9-[1-(3-methylbutyl)piperidin-4-yl]oxy-1,2,4,6-tetrahydrothiopyrano[3,4-c]quinolin-5-one
CFAMM00453226 CHEMBL1092776 Bioactive SureCN8040578
CFAMM00453225 CHEMBL1093295 Bioactive SureCN8040577

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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