CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19815
Family Name Beta-secretase 1 and Amyloid beta A4 protein inhibitor SureCN3014953 family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00453252 Functional Category Bioactive
Superfamily Beta-secretase 1 and Amyloid beta A4 protein Binder Superfamily
Class Class 2014

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Tyrosine-protein kinase Lck inhibitor 4-N-(2-chloro-6-methylph... 8 45
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Su... 2 16
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 9 19
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Corticotropin-releasing factor receptor 1 ligand 5-(2-chloro-4... 7 1
Insulin-like growth factor 1 receptor and Potassium voltage-ga... 2 2
Hepatocyte growth factor receptor ligand [3,5-dichloro-4-[4-(3... 1 1
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 2
Insulin-like growth factor 1 receptor ligand 3-[8-amino-1-(4-e... 9 0
Glucagon receptor ligand SureCN2647807 family 3 7
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 7 4
Fibroblast growth factor receptor 1 and Proto-oncogene tyrosin... 2 0
Neuropeptide S receptor ligand 5-(4-chlorophenyl)-6-methoxy-5-... 4 0
Metabotropic glutamate receptor 5 ligand AGN-PC-0760YR family 1 0
Bifunctional epoxide hydrolase 2 and Arachidonate 5-lipoxygena... 3 0


External ID

Functional Category

Molecule Name

CFAMM00453252 CHEMBL1090542 Bioactive SureCN3014953

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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