CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19820
Family Name Sterol O-acyltransferase 1 inhibitor SureCN6152927 family
No. of Seeds 7 No. of Other Members 3
Family Centroid CFAMM00453283 Functional Category Bioactive
Superfamily Renin Inhibitor Ro-66-1168 Superfamily
Class Class 833

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 6
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 9 37
Transient receptor potential cation channel subfamily V member... 3 15
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2I family 3 3
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2K family 2 0
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
Melanin-concentrating hormone receptor 1 ligand 3-[4-fluoro-3-... 3 7
C-X-C chemokine receptor type 3 ligand 1-[1-[(9-acetyl-9-azabi... 1 0
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand (6aR,... 1 4
C-C chemokine receptor type 3 ligand SureCN6700764 family 2 2
C-X-C chemokine receptor type 3 ligand 1-[1-[[(1S,5R)-6,6-dime... 2 3
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9818603 f... 2 2
Cholinesterase inhibitor (13-methyl-5,6,8,13a-tetrahydroisoqui... 1 0


External ID

Functional Category

Molecule Name

CFAMM00453279 CHEMBL574473 Bioactive AGN-PC-07CO2K
CFAMM00453277 CHEMBL584180 Bioactive AGN-PC-07CO2B
CFAMM00453283 CHEMBL1091036 Bioactive SureCN6152927
CFAMM00453276 CHEMBL573802 Bioactive AGN-PC-07CO2I
CFAMM00453282 CHEMBL503766 Bioactive AGN-PC-077SI0
CFAMM00453281 CHEMBL574388 Bioactive AGN-PC-07CO2N
CFAMM00453274 CHEMBL442567 Bioactive AGN-PC-077SGO

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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