CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1983
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 inhibitor Hydroxamate 34 family
No. of Seeds 12 No. of Other Members 49
Family Centroid CFAMM00329264 Functional Category Bioactive
Superfamily Neutrophil collagenase and 72 kDa type IV collagenase Binder Superfamily
Class Class 3481

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor PXD101 Family 3 24
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 7
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 8 4
Pol polyprotein inhibitor Lysine Sulfonamide 14a family 12 3
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-2-[ben... 2 12
Microbial collagenase inhibitor AGN-PC-074HKS family 4 3
Neutrophil collagenase and Matrix metalloproteinase-9 inhibito... 4 1
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 10 3
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 7 0
Interstitial collagenase and 72 kDa type IV collagenase inhibi... 2 0
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 0
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 2 2
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 2 0
Microbial collagenase inhibitor AGN-PC-00F1J7 family 4 2
Microbial collagenase inhibitor AGN-PC-074HB8 family 3 0
Peptide deformylase inhibitor 2-(5-bromo-2,2-dioxo-1,4-dihydro... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00329265 CHEMBL306726 Bioactive Hydroxamate 38
CFAMM00329285 CHEMBL123775 Bioactive Hydroxamate 41
CFAMM00329311 CHEMBL54054 Bioactive N-hydroxy-2-[(4-nitrophenyl)methyl-[3-(trifluoromethyl)phenyl]sulfonylamino]acetamide
CFAMM00329264 CHEMBL55110 Bioactive Hydroxamate 34
CFAMM00329297 CHEMBL54904 Bioactive 2-[1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctylsulfonyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamide
CFAMM00329290 CHEMBL293503 Bioactive Hydroxamate 35
CFAMM00329283 CHEMBL122711 Bioactive N-hydroxy-2-[(2-nitrophenyl)methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetamide
CFAMM00329302 CHEMBL122836 Bioactive Hydroxamate 40
CFAMM00329260 CHEMBL303388 Bioactive AGN-PC-074HCZ
CFAMM00329259 CHEMBL330040 Bioactive AGN-PC-074PXC
CFAMM00329280 CHEMBL122719 Bioactive N-hydroxy-2-[(2-nitrophenyl)methyl-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonyl)amino]acetamide
CFAMM00329273 CHEMBL304281 Bioactive Hydroxamate 37

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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