CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19849
Family Name Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC-07ZEXL family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00453394 Functional Category Bioactive
Superfamily Cathepsin S and Cathepsin L1 Binder Superfamily
Class Class 3305

Cousin Family NamesSeedsMembers
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 8 1
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Neuromedin-K receptor ligand 3-methylsulfinyl-N-[(1S)-1-phenyl... 3 5
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3-fluo... 6 4
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzen... 4 4
C-X-C chemokine receptor type 3 ligand AGN-PC-07ZH3V family 1 1
Secreted frizzled-related protein 1 inhibitor AGN-PC-07R8UU fa... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00453396 CHEMBL1096820 Bioactive AGN-PC-07ZEUB
CFAMM00453394 CHEMBL1095531 Bioactive AGN-PC-07ZEXL

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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