CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19853
Family Name Sodium-dependent noradrenaline transporter and Sodium-dependent dopamine transporter inhibitor Cyclohexanol, 1-[1-(3-chlorophenyl)-2-(4-methyl-1-piperazinyl)ethyl]- family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00453406 Functional Category Bioactive
Superfamily Histamine H1 receptor Ligand Chlophedianol Superfamily
Class Class 225

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor Ligand Chlophedianol Family 4 46
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
D(2) dopamine receptor and D(3) dopamine receptor ligand 4-(4-... 1 3
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 6 3
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-04... 1 0
D(1A) dopamine receptor and D(3) dopamine receptor ligand (2S,... 5 5
C-C chemokine receptor type 1 ligand SureCN9108276 family 1 0
C-C chemokine receptor type 1 ligand SureCN9108965 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00453408 CHEMBL511525 Bioactive 1-[(1S)-1-(3-chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexan-1-ol;dihydrochloride
CFAMM00453414 CHEMBL1099179 Bioactive SureCN4975031
CFAMM00453413 CHEMBL461705 Bioactive AGN-PC-007BWN
CFAMM00453406 CHEMBL1096495 Bioactive Cyclohexanol, 1-[1-(3-chlorophenyl)-2-(4-methyl-1-piperazinyl)ethyl]-
CFAMM00453411 CHEMBL461707 Bioactive SureCN3980403
CFAMM00453409 CHEMBL511347 Bioactive WY-46824

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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