CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19880
Family Name Microtubule-associated protein tau and Glycogen synthase kinase-3 alpha inhibitor Indirubin family
No. of Seeds 9 No. of Other Members 15
Family Centroid CFAMM00453486 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Cyclin-dependent kinase 1 Binder Superfamily
Class Class 5353

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 2 5
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 1 1
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 2 2
Survival motor neuron protein and Arachidonate 15-lipoxygenase... 1 2
Mitogen-activated protein kinase 14 inhibitor AGN-PC-08866Z fa... 2 0
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 1 0
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 2 10
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 1 1


External ID

Functional Category

Molecule Name

CFAMM00453501 CHEMBL173445 Bioactive 5'-Iodoindirubin
CFAMM00453493 CHEMBL174343 Bioactive indirubin deriv. 5c
CFAMM00453486 CHEMBL35349 Bioactive Indirubin
CFAMM00453505 CHEMBL111433 Bioactive SureCN13879091
CFAMM00453504 CHEMBL176904 Bioactive indirubin deriv. 5a
CFAMM00453483 CHEMBL173682 Bioactive BRY
CFAMM00453496 CHEMBL174025 Bioactive NSC717813
CFAMM00453489 CHEMBL367113 Bioactive NSC717815
CFAMM00453482 CHEMBL367345 Bioactive NSC717814

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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