CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19890
Family Name Glycogen synthase kinase-3 beta inhibitor 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-pyridin-4-ylmethylideneamino]-5-(pyrrolidin-1-ylmethyl)triazole-4-carboxamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00453530 Functional Category Bioactive
Superfamily Menin and Ferritin light chain Binder Superfamily 7
Class Class 3234

Cousin Family NamesSeedsMembers
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 1
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 4
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Aurora kinase B and Aurora kinase A inhibitor (2S)-1-[4-[[1-[(... 12 4
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... 6 0
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00453531 CHEMBL325353 Bioactive ST073749
CFAMM00453530 CHEMBL113272 Bioactive 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-pyridin-4-ylmethylideneamino]-5-(pyrrolidin-1-ylmethyl)triazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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