CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19898
Family Name Integrin beta-3 and Integrin alpha-IIb inhibitor 4-[[4-(4-carbamimidoylphenyl)-1,3-thiazol-2-yl]-[1-(carboxymethyl)piperidin-4-yl]amino]butanoic acid family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00453578 Functional Category Bioactive
Superfamily Aldose reductase Inhibitor SPR-210 Superfamily
Class Class 1647

Cousin Family NamesSeedsMembers
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Prostaglandin D2 receptor 2 ligand AGN-PC-0143RG family 6 13
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-t... 3 4
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 6 9
Sphingosine kinase 1 and Sphingosine kinase 2 inhibitor (2R,4S... 9 8
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dih... 11 0
Diacylglycerol O-acyltransferase 1 inhibitor (1R,2R)-2-[4-[3-f... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00453579 CHEMBL114589 Bioactive SureCN3497287
CFAMM00453578 CHEMBL116436 Bioactive 4-[[4-(4-carbamimidoylphenyl)-1,3-thiazol-2-yl]-[1-(carboxymethyl)piperidin-4-yl]amino]butanoic acid
CFAMM00453576 CHEMBL114329 Bioactive 2-[4-[[4-(4-carbamimidoylphenyl)-1,3-thiazol-2-yl]amino]piperidin-1-yl]-4-methoxy-4-oxobutanoic acid
CFAMM00453581 CHEMBL115775 Bioactive 2-[4-[[4-(4-carbamimidoylphenyl)-1,3-thiazol-2-yl]amino]piperidin-1-yl]-2-phenylacetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27747 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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