CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1990
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor (2S)-2-[[4-[(E)-2-imidazol-1-ylethenyl]-2-(2-methylphenyl)benzoyl]amino]-4-methylsulfanylbutanoic acid family
No. of Seeds 4 No. of Other Members 8
Family Centroid CFAMM00329362 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Binder Superfamily 2
Class Class 1170

Cousin Family NamesSeedsMembers
Eluxadoline family 4 85
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 17 14
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 11 22
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 5 14
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Cannabinoid receptor 1 ligand N-(cyclobutylmethyl)-3-[[4-(meth... 1 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor (2S)-2... 2 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00329362 CHEMBL159400 Bioactive (2S)-2-[[4-[(E)-2-imidazol-1-ylethenyl]-2-(2-methylphenyl)benzoyl]amino]-4-methylsulfanylbutanoic acid
CFAMM00329355 CHEMBL159764 Bioactive SureCN7605448
CFAMM00329365 CHEMBL122882 Bioactive (2S)-2-[[4-[[benzyl(pyrazin-2-yl)amino]methyl]-2-(2-methylphenyl)benzoyl]amino]-4-methylsulfanylbutanoic acid
CFAMM00329364 CHEMBL123339 Bioactive (2S)-2-[[4-[[benzyl(pyrimidin-5-yl)amino]methyl]-2-(2-methylphenyl)benzoyl]amino]-4-methylsulfanylbutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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