CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19901
Family Name Thromboxane-A synthase inhibitor ethyl 5-[(Z)-[pyridin-3-yl-[3-[[4-(2-pyridin-3-yl-1,3-thiazolidine-4-carbonyl)piperazin-1-yl]methyl]phenyl]methylidene]amino]oxypentanoate family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00453586 Functional Category Bioactive
Superfamily Pol polyprotein and Thromboxane-A synthase Binder Superfamily
Class Class 189

Cousin Family NamesSeedsMembers
Pol polyprotein inhibitor penicillin deriv. 40 family 2 4
Platelet-activating factor receptor ligand YM-461 family 1 11
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(4-quinolin-4-ylpi... 5 8
Voltage-dependent N-type calcium channel subunit alpha-1B liga... 2 1


External ID

Functional Category

Molecule Name

CFAMM00453586 CHEMBL114843 Bioactive ethyl 5-[(Z)-[pyridin-3-yl-[3-[[4-(2-pyridin-3-yl-1,3-thiazolidine-4-carbonyl)piperazin-1-yl]methyl]phenyl]methylidene]amino]oxypentanoate
CFAMM00453590 CHEMBL324118 Bioactive ethyl 5-[(E)-[pyridin-3-yl-[4-[[4-(2-pyridin-3-yl-1,3-thiazolidine-4-carbonyl)piperazin-1-yl]methyl]phenyl]methylidene]amino]oxypentanoate
CFAMM00453589 CHEMBL539177 Bioactive ethyl 5-[(E)-[pyridin-3-yl-[4-[4-(2-pyridin-3-yl-1,3-thiazolidine-4-carbonyl)piperazine-1-carbonyl]phenyl]methylidene]amino]oxypentanoate
CFAMM00453588 CHEMBL117889 Bioactive ethyl 5-[(E)-[pyridin-3-yl-[3-[4-(2-pyridin-3-yl-1,3-thiazolidine-4-carbonyl)piperazine-1-carbonyl]phenyl]methylidene]amino]oxypentanoate
CFAMM00453587 CHEMBL324533 Bioactive 5-[(Z)-[pyridin-3-yl-[3-[[4-(2-pyridin-3-yl-1,3-thiazolidine-4-carbonyl)piperazin-1-yl]methyl]phenyl]methylidene]amino]oxypentanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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