CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19906
Family Name Gonadotropin-releasing hormone receptor ligand N-[[4-[(diaminomethylideneamino)methyl]cyclohexyl]methyl]-5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]furan-2-carboxamide family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00453628 Functional Category Bioactive with Natural Product
Superfamily Integrin beta-3 and Integrin alpha-IIb Binder Superfamily 23
Class Class 1691

Cousin Family NamesSeedsMembers
Histone deacetylase Inhibitor Abexinostat Family 1 20
Histamine H3 receptor Ligand A-317920 Family 9 240
Histamine H3 receptor Ligand A-349821 Family 49 228
Estradiol 17-beta-dehydrogenase 1 Inhibitor N(furan-2-ylmethyl... 2 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 33
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Fatty-acid amide hydrolase 1 Inhibitor Furan-2-ylmethylcarbami... 1 105
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Substance-K receptor ligand 5-chloro-N-[1-[[(2S)-5-[4-(oxan-4-... 2 4
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 4
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6
Prostaglandin E2 receptor EP4 subtype ligand SureCN5653729 family 3 2
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Histamine H3 receptor ligand SureCN5218144 family 4 6
Kappa-type opioid receptor ligand methyl (2S,4aR,6aR,7R,9S,10a... 5 19
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 4 13
Trypsin-1 and Prothrombin inhibitor CHEMBL297536 family 1 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00AWDS ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00453633 CHEMBL445074 Bioactive AGN-PC-034WEW
CFAMM00453630 CHEMBL331277 Bioactive methyl 4-[[[5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]furan-2-carbonyl]amino]methyl]cyclohexane-1-carboxylate
CFAMM00453622 CHEMBL332923 Bioactive AGN-PC-034WFM
CFAMM00453629 CHEMBL323863 Bioactive AGN-PC-034YGM
CFAMM00453628 CHEMBL115482 Bioactive N-[[4-[(diaminomethylideneamino)methyl]cyclohexyl]methyl]-5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]furan-2-carboxamide
CFAMM00453627 CHEMBL117170 Bioactive N-[(4-cyanocyclohexyl)methyl]-5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]furan-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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