CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19911
Family Name Caspase-1 inhibitor 3-[[(2S)-4-hydroxy-1-[(2S)-3-methyl-2-[[(E)-3-phenylprop-2-enyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-4-oxo-5-phenoxypentanoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00453649 Functional Category Bioactive
Superfamily Plitidepsin Superfamily
Class Class 412

Cousin Family NamesSeedsMembers
Thymopentin family 20 133
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Plitidepsin family 15 5
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Caspase-6 and Caspase-3 inhibitor (4S)-5-[[1-[[(3S)-2-hydroxy-... 1 24
Histamine H3 receptor ligand SureCN4319687 family 8 15
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Renin inhibitor (3S,6R)-6-(cyclohexylmethyl)-7-hydroxy-7-[[(2S... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2R)-3-[4-(2-me... 18 1
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
Pol polyprotein inhibitor (3S)-N-tert-butyl-2-[(2R)-2-[(3S,6S,... 3 1
Caspase-1 inhibitor 3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethox... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00453649 CHEMBL115823 Bioactive 3-[[(2S)-4-hydroxy-1-[(2S)-3-methyl-2-[[(E)-3-phenylprop-2-enyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-4-oxo-5-phenoxypentanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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