CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1997
Family Name Growth hormone secretagogue receptor type 1 ligand (E)-5-amino-N-[(2R)-1-[[(2R)-1-[[(2S)-2-hydroxypropyl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]-methylamino]-1-oxo-3-(4-phenylcyclohexa-1,5-dien-1-yl)propan-2-yl]-N,5-dimethylhex-2-enamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00329404 Functional Category Bioactive
Superfamily Plasmepsin-2 Inhibitor KNI-10232 Superfamily
Class Class 2411

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Renin Inhibitor CP-80794 Family 16 112
Pol polyprotein inhibitor 169168-45-0 family 7 11
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 4 2
Growth hormone secretagogue receptor type 1 ligand SureCN76469... 4 4
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 3 3
Growth hormone secretagogue receptor type 1 ligand (2S)-2,6-di... 2 1
Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-a... 6 3
Renin inhibitor 4BALMORPH family 1 0


External ID

Functional Category

Molecule Name

CFAMM00329404 CHEMBL122939 Bioactive (E)-5-amino-N-[(2R)-1-[[(2R)-1-[[(2S)-2-hydroxypropyl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]-methylamino]-1-oxo-3-(4-phenylcyclohexa-1,5-dien-1-yl)propan-2-yl]-N,5-dimethylhex-2-enamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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