CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19984
Family Name Mitogen-activated protein kinase 14 inhibitor 4-(4-fluorophenyl)-5-[2-[(4-hydroxycyclohexyl)amino]pyridin-4-yl]-1,3-dihydroimidazol-2-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00453930 Functional Category Bioactive
Superfamily Adenosine receptor A1 Ligand SLV320 Superfamily
Class Class 1134

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Adenosine receptor A1 Ligand SLV320 Family 6 79
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 6
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 2 5
Neuropeptide Y receptor type 5 ligand (5E)-5-[(4S,5S)-4-(4-flu... 18 3
Tyrosine-protein kinase ITK/TSK and Aurora kinase B inhibitor ... 1 1


External ID

Functional Category

Molecule Name

CFAMM00453930 CHEMBL1172017 Bioactive 4-(4-fluorophenyl)-5-[2-[(4-hydroxycyclohexyl)amino]pyridin-4-yl]-1,3-dihydroimidazol-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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