CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19988
Family Name Thrombopoietin receptor ligand (4R)-1-[3-chloro-5-[[4-[2-fluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]carbamoyl]pyridin-2-yl]-4-methylpyrrolidine-3-carboxylic acid family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00453949 Functional Category Bioactive
Superfamily Cholecystokinin receptor type A Ligand Lintitript Superfamily
Class Class 888

Cousin Family NamesSeedsMembers
Thrombopoietin receptor Ligand AKR-501 Family 2 8
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1


External ID

Functional Category

Molecule Name

CFAMM00453949 CHEMBL461174 Bioactive (4R)-1-[3-chloro-5-[[4-[2-fluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]carbamoyl]pyridin-2-yl]-4-methylpyrrolidine-3-carboxylic acid
CFAMM00453954 CHEMBL524116 Bioactive (2R)-2-[[3-chloro-5-[[4-[2-fluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]carbamoyl]pyridin-2-yl]amino]propanoic acid
CFAMM00453944 CHEMBL1172354 Bioactive AGN-PC-080TUS

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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