CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2
Family Name Pol polyprotein inhibitor 169168-45-0 family
No. of Seeds 7 No. of Other Members 11
Family Centroid CFAMM00305750 Functional Category Bioactive
Superfamily Renin and Pol polyprotein Binder Superfamily
Class Class 168

Cousin Family NamesSeedsMembers
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Renin Inhibitor CP-80794 Family 16 112
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Pol polyprotein inhibitor 169273-51-2 family 10 0
Pol polyprotein inhibitor AC1LA3TO family 8 0
Beta-secretase 1 inhibitor N-[(1S,2S)-3-(3,5-difluorophenyl)-1... 1 2
Growth hormone secretagogue receptor type 1 ligand (E)-5-amino... 1 1
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Pol polyprotein inhibitor benzyl N-[(2S,3R)-4-[(3aR,6S,7aS)-6-... 3 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-cycl... 1 6
Pol polyprotein inhibitor Sulfone deriv. 31 family 15 4
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 16 1
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 3 3
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 6 11
Beta-secretase 1 and Cathepsin B inhibitor SureCN4666465 family 9 4
Cathepsin E and Renin inhibitor (2S)-N-[2-[[(2S,3S,5S)-1-cyclo... 4 0
Beta-secretase 1 and Cathepsin B inhibitor 3-chloro-N-[(2S)-1-... 2 0
Renin inhibitor (1R,2R,3S)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl... 5 0
Pol polyprotein inhibitor AC1LAH8S family 11 1
Pol polyprotein inhibitor TYB5 family 2 0
Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-h... 2 0
Pol polyprotein inhibitor AC1LA3V9 family 2 1
Renin inhibitor 4BALMORPH family 1 0
Pol polyprotein inhibitor AC1LACBC family 2 0
Renin and Cathepsin D inhibitor (2S)-N-[(2S)-3-(5-aminothiophe... 1 0
Renin inhibitor MRM-HFA-CYM-CPY family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00305743 CHEMBL98954 Bioactive 169168-43-8
CFAMM00305742 CHEMBL328205 Bioactive 169168-44-9
CFAMM00305735 CHEMBL100040 Bioactive 169168-68-7
CFAMM00305734 CHEMBL317793 Bioactive Saquinavir/Nelfinavir deriv. 11
CFAMM00305733 CHEMBL99878 Bioactive 169168-50-7
CFAMM00305745 CHEMBL318668 Bioactive LY314163
CFAMM00305750 CHEMBL431455 Bioactive 169168-45-0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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