CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20
Family Name Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00GNZ0 family
No. of Seeds 16 No. of Other Members 4
Family Centroid CFAMM00244128 Functional Category Bioactive
Superfamily Estrogen receptor and Estrogen receptor beta Binder Superfamily
Class Class 833

Cousin Family NamesSeedsMembers
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Acetylcholinesterase Inhibitor Edrophonium Family 7 40
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Cholesteryl ester transfer protein Inhibitor CP-800569 Family 5 81
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Cholesteryl ester transfer protein Inhibitor Tetrahydroquinoli... 3 8
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(4-... 3 5
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 8 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 8
Estrogen receptor and Estrogen receptor beta ligand SureCN5681... 7 3
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Translocator protein inhibitor [11C]DAA1106 family 15 2
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
5-hydroxytryptamine receptor 7 ligand 1-(2-methoxyphenyl)-4-[2... 6 2
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 2
D(3) dopamine receptor and D(2) dopamine receptor ligand (5R)-... 2 0
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 2
5-hydroxytryptamine receptor 1A ligand AGN-PC-0034EG family 5 2
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26
5-hydroxytryptamine receptor 1A ligand (1R,2R)-2-[4-(2,3-dihyd... 2 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Estrogen receptor and Estrogen receptor beta ligand SureCN6716... 2 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Estrogen receptor beta and Estrogen receptor ligand (E)-3-[4-(... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00305979 CHEMBL319678 Bioactive 2-(3-chlorophenyl)-1-methyl-1-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-3,4-dihydroisoquinolin-6-ol
CFAMM00305978 CHEMBL98470 Bioactive 1-methyl-2-(4-propan-2-ylphenyl)-1-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-3,4-dihydroisoquinolin-6-ol
CFAMM00305976 CHEMBL100231 Bioactive AGN-PC-00EZY6
CFAMM00305981 CHEMBL100763 Bioactive 2-(4-chlorophenyl)-1-methyl-1-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-3,4-dihydroisoquinolin-6-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26241 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543