CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20009
Family Name Thromboxane-A synthase and Thromboxane A2 receptor ligand Fce 27262 family
No. of Seeds 12 No. of Other Members 20
Family Centroid CFAMM00454041 Functional Category Bioactive
Superfamily Telomerase protein component 1 Inhibitor GRN163L Superfamily
Class Class 874

Cousin Family NamesSeedsMembers
Thromboxane-A synthase Inhibitor CGS-13080 Family 3 19


External ID

Functional Category

Molecule Name

CFAMM00454058 CHEMBL120250 Bioactive 5-[(E)-[1-cyclohexyl-2-imidazol-1-yl-3-(4-methylphenyl)propylidene]amino]oxypentanoic acid
CFAMM00454064 CHEMBL122123 Bioactive 5-[(Z)-(2-imidazol-1-yl-1,3-diphenylpropylidene)amino]oxypentanoic acid
CFAMM00454041 CHEMBL120181 Bioactive Fce 27262
CFAMM00454040 CHEMBL120041 Bioactive Cifaop
CFAMM00454062 CHEMBL275256 Bioactive 5-[(E)-[1-cyclohexyl-2-imidazol-1-yl-3-[4-(trifluoromethyl)phenyl]propylidene]amino]oxypentanoic acid
CFAMM00454068 CHEMBL333237 Bioactive 5-[(E)-[1-cyclohexyl-3-(3-fluorophenyl)-2-imidazol-1-ylpropylidene]amino]oxypentanoic acid
CFAMM00454048 CHEMBL120019 Bioactive 5-[(E)-(2-imidazol-1-yl-1-phenylnonan-3-ylidene)amino]oxypentanoic acid
CFAMM00454061 CHEMBL118188 Bioactive 5-[(E)-[3-(4-fluorophenyl)-2-imidazol-1-yl-1-phenylpropylidene]amino]oxypentanoic acid
CFAMM00454054 CHEMBL339877 Bioactive 5-[(E)-[3-(4-chlorophenyl)-2-imidazol-1-yl-1-phenylpropylidene]amino]oxypentanoic acid
CFAMM00454067 CHEMBL444856 Bioactive AC1NX7ZH
CFAMM00454047 CHEMBL122008 Bioactive 5-[(Z)-[3-(4-fluorophenyl)-2-imidazol-1-yl-1-phenylpropylidene]amino]oxypentanoic acid
CFAMM00454060 CHEMBL118184 Bioactive 5-[(E)-(2-imidazol-1-yl-1,3-diphenylpropylidene)amino]oxypentanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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