CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20020
Family Name Heme oxygenase 1 and Heme oxygenase 2 inhibitor 1-imidazol-1-yl-4-(4-iodophenyl)butan-2-ol family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00454142 Functional Category Bioactive
Superfamily Cytochrome P450 2D6 and Cytochrome P450 11B1, mitochondrial Binder Superfamily
Class Class 2308

Cousin Family NamesSeedsMembers
14-alpha sterol demethylase inhibitor imidazole derivative Mi... 6 59
14-alpha sterol demethylase Inhibitor Butoconazole Family 2 53
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
Cytochrome P450 2D6 Inhibitor GBR-12289 Family 1 0
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Rac-4'-(1-i... 5 9
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 6 6
Cytochrome P450 11B1, mitochondrial Inhibitor (3-((1h-imidazol... 2 5
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 2 8
Heme oxygenase 1 and Heme oxygenase 2 inhibitor imidazole-diox... 2 15


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00454144 CHEMBL536746 Bioactive SureCN412035
CFAMM00454142 CHEMBL1188560 Bioactive 1-imidazol-1-yl-4-(4-iodophenyl)butan-2-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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