CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2006
Family Name Aurora kinase A inhibitor SureCN3894803 family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00329460 Functional Category Bioactive
Superfamily Menin and Aurora kinase A Binder Superfamily
Class Class 2270

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Family 6 29
Cyclin-dependent kinase 2 Inhibitor N-(5-cyclopropyl-1h-pyrazo... 6 62
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Poly [ADP-ribose] polymerase 1 inhibitor 2-[2-[4-(1H-indazol-3... 1 0
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-0A9SI... 4 0
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 2 6
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 4 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4


External ID

Functional Category

Molecule Name

CFAMM00329461 CHEMBL1257296 Bioactive SureCN3891045
CFAMM00329462 CHEMBL1257180 Bioactive SureCN3880858
CFAMM00329460 CHEMBL1230201 Bioactive SureCN3894803
CFAMM00329453 CHEMBL2376496 Bioactive 3-[[4-(4-methylpiperazin-1-yl)benzoyl]amino]-N-(2-phenylpropan-2-yl)-2H-thieno[2,3-c]pyrazole-5-carboxamide
CFAMM00329455 CHEMBL1258912 Bioactive SureCN3881690

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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