CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20061
Family Name Inhibitor of nuclear factor kappa-B kinase subunit beta inhibitor AGN-PC-042IPJ family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00454420 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 1 and Binder Superfamily
Class Class 427

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 12 85
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 12
Lutropin-choriogonadotropic hormone receptor and Follicle-stim... 1 3
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1


External ID

Functional Category

Molecule Name

CFAMM00454430 CHEMBL565347 Bioactive SureCN4656920
CFAMM00454420 CHEMBL570276 Bioactive AGN-PC-042IPJ
CFAMM00454419 CHEMBL1204404 Bioactive 3-amino-6-(4-hydroxy-3,3-dimethylpiperidin-1-yl)-4-propylthieno[2,3-b]pyridine-2-carboxamide;hydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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