CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20063
Family Name Arachidonate 5-lipoxygenase inhibitor methyl 5-[1-(2-butyl-1-benzofuran-5-yl)ethyl-hydroxyamino]-5-oxopentanoate family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00454442 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 and D(2) dopamine receptor Binder Superfamily
Class Class 2912

Cousin Family NamesSeedsMembers
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hy... 3 9
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Endothelin-1 receptor and Endothelin B receptor ligand (2R,3R,... 3 2
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 12 0
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
Arachidonate 5-lipoxygenase inhibitor 1-hydroxy-1-[1-[2-(3,4,5... 2 2
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00454437 CHEMBL332174 Bioactive methyl 5-[hydroxy-[1-(2-phenyl-1-benzofuran-5-yl)ethyl]amino]-5-oxopentanoate
CFAMM00454442 CHEMBL120672 Bioactive methyl 5-[1-(2-butyl-1-benzofuran-5-yl)ethyl-hydroxyamino]-5-oxopentanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27433 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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