CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM201
Family Name Beta-1 adrenergic receptor and Beta-2 adrenergic receptor ligand 1,2-benzenediol, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3-fluoro-,( inverted exclamation markA)- family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00308846 Functional Category Bioactive
Superfamily Muscarinic acetylcholine receptor M2 Ligand Gallamine Triethiodide Superfamily
Class Class 576

Cousin Family NamesSeedsMembers
Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Beta-1 adrenergic receptor Ligand Oxprenolol Family 3 27
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Muscarinic acetylcholine receptor M2 Ligand Gallamine Triethio... 1 14
5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
Beta-3 adrenergic receptor Ligand ZD7114 Family 1 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Leukotriene A-4 hydrolase Inhibitor (r/s)-2-((4-phenoxyphenoxy... 7 18
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 7 8
Alpha-1A adrenergic receptor and 5-hydroxytryptamine receptor ... 1 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 7
Squalene synthase inhibitor [4-[3-(propan-2-ylamino)propoxy]ph... 1 3
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308846 CHEMBL10453 Bioactive 1,2-benzenediol, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3-fluoro-,( inverted exclamation markA)-
CFAMM00308845 CHEMBL266619 Bioactive AC1LBLAW

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21794 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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