CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-aminobutyric acid receptor subunit beta-1 ligand 6-thiophen-3-yl-3-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[1,5-a]pyrimidin-7-one family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00308847 Functional Category Bioactive
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 2
Class Class 3101

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23


External ID

Functional Category

Molecule Name

CFAMM00308856 CHEMBL440150 Bioactive 3-(3-bromophenyl)-6-thiophen-3-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
CFAMM00308847 CHEMBL322313 Bioactive 6-thiophen-3-yl-3-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
CFAMM00308851 CHEMBL104568 Bioactive 3-pyridin-2-yl-6-thiophen-3-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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