CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2021
Family Name MAP kinase-activated protein kinase 2 inhibitor CHEMBL1231206 family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00329626 Functional Category Bioactive
Superfamily Substance-K receptor and MAP kinase-activated protein kinase 2 Binder Superfamily
Class Class 3155

Cousin Family NamesSeedsMembers
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Deoxycytidine kinase inhibitor N-[(1S,3S)-3-(4-amino-5-fluoro-... 2 5
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-1-phenyl-5-[4... 4 0
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1367658 ... 1 7
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Neuromedin-K receptor ligand 3-methylsulfinyl-N-[(1S)-1-phenyl... 3 5
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00329619 CHEMBL560075 Bioactive CHEMBL560075
CFAMM00329625 CHEMBL556392 Bioactive CHEMBL556392
CFAMM00329618 CHEMBL564076 Bioactive CHEMBL564076
CFAMM00329616 CHEMBL561334 Bioactive CHEMBL561334
CFAMM00329622 CHEMBL549915 Bioactive CHEMBL549915
CFAMM00329626 CHEMBL1231206 Bioactive CHEMBL1231206

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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