CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20231
Family Name Sterol 26-hydroxylase, mitochondrial and 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial inhibitor AGN-PC-080IGW family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00455028 Functional Category Bioactive
Superfamily Multidrug resistance-associated protein 1 Inhibitor Benzbromarone Superfamily
Class Class 957

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 3
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Arachidonate 5-lipoxygenase Inhibitor 4,5-dimethoxy-10h-anthra... 1 4
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-b... 6 21
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Acetylcholinesterase inhibitor AGN-PC-003A5N family 3 9
Amine oxidase [flavin-containing] B inhibitor 5-(4,4,4-trifluo... 2 9
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 7 13
NAD-dependent protein deacetylase sirtuin-2 inhibitor 8-bromo-... 1 0
Acenes Metabolite Lacinilene C Family 2 3
Naphthofurans Metabolite Pyrocurzerenone Family 1 9
NP 7-[(4-bromobenzyl)oxy]-3-(2-methoxyphenyl)-2-(trifluorometh... 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00455028 CHEMBL1253946 Bioactive AGN-PC-080IGW

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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