CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20256
Family Name Metabotropic glutamate receptor 5 ligand SureCN504754 family
No. of Seeds 5 No. of Other Members 4
Family Centroid CFAMM00455158 Functional Category Bioactive
Superfamily C-C chemokine receptor type 3 and Metabotropic glutamate receptor 5 Binder Superfamily
Class Class 994

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand R 673 Family 2 127
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family 2 8
Metabotropic glutamate receptor 5 ligand 3-fluoro-5-(5-pyridin... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00455160 CHEMBL1257274 Bioactive SureCN504565
CFAMM00455158 CHEMBL1257273 Bioactive SureCN504754
CFAMM00455157 CHEMBL1258893 Bioactive SureCN504860
CFAMM00455163 CHEMBL1257505 Bioactive AGN-PC-07ZPRM
CFAMM00455162 CHEMBL1257504 Bioactive SureCN504696

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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