CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20275
Family Name Lysosomal Pro-X carboxypeptidase inhibitor 1-[(2S)-2-[5-(3-bromophenyl)-1H-imidazol-2-yl]-4,4-difluoropyrrolidin-1-yl]-3-[4-(2,3-dichlorophenyl)phenyl]-2,2-dimethylpropan-1-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00455223 Functional Category Bioactive
Superfamily Lysosomal Pro-X carboxypeptidase Binder Superfamily
Class Class 1016

Cousin Family NamesSeedsMembers
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Lysosomal Pro-X carboxypeptidase inhibitor 2-amino-N-[(2S)-1-[... 11 16
Coagulation factor X inhibitor SureCN8289965 family 4 5
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Lysosomal Pro-X carboxypeptidase inhibitor 3-[4-[3-[(2S,4R)-2-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00455223 CHEMBL1259085 Bioactive 1-[(2S)-2-[5-(3-bromophenyl)-1H-imidazol-2-yl]-4,4-difluoropyrrolidin-1-yl]-3-[4-(2,3-dichlorophenyl)phenyl]-2,2-dimethylpropan-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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