CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM20288
Family Name Mitogen-activated protein kinase kinase kinase 11 and Mitogen-activated protein kinase kinase kinase 9 inhibitor Imide Analog 15 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00455262 Functional Category Bioactive
Superfamily DNA topoisomerase 1 and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 5124

Cousin Family NamesSeedsMembers
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Serine/threonine-protein kinase Chk1 Inhibitor BIS-IMIDE A Family 1 3
Nuclear receptor ROR-gamma and Niemann-Pick C1 protein ligand ... 1 12
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
Kinesin-like protein KIF11 inhibitor 9-(trifluoromethyl)-1,2,4... 4 1
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL246396 family 22 0


External ID

Functional Category

Molecule Name

CFAMM00455262 CHEMBL126545 Bioactive Imide Analog 15

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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